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Fig. 6 | Cancer Cell International

Fig. 6

From: miR-1296-5p decreases ERBB2 expression to inhibit the cell proliferation in ERBB2-positive breast cancer

Fig. 6

MiR-1296-5p sensitizes cells to chemotherapy drugs. a, b Overexpression of miR-1296 in SK-BR-3 or BT-474 breast cancer cells significantly sensitized cells to cisplatin and 5-fluorouracil (5-FU) treatment as compared to control miRNA. Cells were treated with cisplatin 24 h following miR-1296-5p transfection and the cell viability was assessed after 48 h of cisplatin treatment. 5-FU, 5-fluorouracil. HCPT, hydroxy camptothecin. ns no significance

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