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Fig. 2 | Cancer Cell International

Fig. 2

From: miR-155-5p modulates malignant behaviors of hepatocellular carcinoma by directly targeting CTHRC1 and indirectly regulating GSK-3β-involved Wnt/β-catenin signaling

Fig. 2

CTHRC1 is a direct target of miR-155-5p. a A graphical representation of miR-155-5p -binding sites in the wild-type CTHRC1-3′-UTR and mutant CTHRC1-3′-UTR. b Dual-luciferase reporter assay was performed in 293T cells, and the data are presented as the mean ± SD. **p < 0.01. c miR-155-5p expression was examined by qRT-PCR in 293T cells after transfection with NC and miR-155-5p mimic plasmids. *p < 0.05. d CTHRC1 mRNA expression was determined by qRT-PCR in 293T cells after transfecting with NC and miR-155-5p mimic plasmids. *p < 0.05. e Western blot analysis of CTHRC1 protein levels in the blank, NC and miR-155-5p mimic groups

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Cancer Cell International

ISSN: 1475-2867

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