Fig. 3
From: MiR-20a-5p represses the multi-drug resistance of osteosarcoma by targeting the SDC2 gene
The effects of a forced reversal of the miR-20a-5p mimic (5PM) or si-SDC2 level on the chemoresistance of SJSA-1 cells. a The SDC2 protein level (western blot analysis) in the miR-20a-5p mimic or siRNA-transfected versus the NC-transfected SJSA-1 cells. b The IC50-dosed drug-induced cell death of SJSA-1 cells transfected with the miR-20a-5p mimic (5PM) or si-SDC2 versus the corresponding negative control (NC) assayed 72 h post-treatment. c MiR-20a-5p mimic or si-SDC2-transfected SJSA-1 cells showed lower invasion capacity compared with the NC-transfected. *P value < 0.05, **P value < 0.01 by Student’s t test