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Fig. 4 | Cancer Cell International

Fig. 4

From: Restoration of miR-29b exerts anti-cancer effects on glioblastoma

Fig. 4

Mediators of the effects of miR-29b on glioblastoma cells. a Volcano plots showing miR-29b targeted genes analysed with a PCR array using naïve- and miR-29b-treated A172 cells. The significant candidate targets (fold change > 20) include COL1A2, COL4A1, COL2A1, ITGA11, MMP24, and SPARC. b Network analysis incorporating genes of interest using Pathway Commons (http://www.pathwaycommons.org) shows relationships among the genes. Direct inhibition of SPARC by miR-29b is annotated with a solid line

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