Table 1 Correlation between CMTM 5 expression and clinicopathological variables of 76 HCC patients
Variables | Cases (76) | CMTM5 expression | P value | |
|---|---|---|---|---|
High (17) | Low (59) | |||
Age (years) | ||||
≤ 50 | 47 | 12 (70.6%) | 35 (59.3%) | 0.572 |
> 50 | 29 | 5 (29.4%) | 24 (40.7%) | |
Gender | ||||
Male | 57 | 11 (64.7%) | 46 (77.9%) | 0.266 |
Female | 19 | 6 (35.3%) | 13 (22.1%) | |
AFP (ng/mL) | ||||
≤ 20 | 35 | 7 (41.2%) | 28 (47.5%) | 0.647 |
> 20 | 41 | 10 (58.8%) | 31 (52.5%) | |
ALT (U/mL) | ||||
≤ 75 | 40 | 10 (58.8%) | 30 (50.8%) | 0.564 |
> 75 | 36 | 7 (41.2%) | 29 (49.2%) | |
GGT (U/mL) | ||||
≤ 45 | 43 | 11 (64.7%) | 32 (54.2%) | 0.443 |
> 45 | 33 | 6 (35.3%) | 27 (45.8%) | |
Tumor size (diameter), cm | ||||
≤ 5 | 34 | 10 (58.8%) | 24 (40.7%) | 0.185 |
> 5 | 42 | 7 (41.2%) | 35 (59.3%) | |
Tumor multiplicity | ||||
Single | 53 | 12 (70.6%) | 41 (69.5%) | 0.931 |
Multiple | 23 | 5 (29.4%) | 18 (30.5%) | |
Vascular invasion | ||||
Yes | 20 | 5 (29.4%) | 15 (25.4%) | 0.742 |
No | 56 | 12 (70.6%) | 44 (74.6%) | |
Tumor differentiation | ||||
I–II | 57 | 16 (94.1%) | 41 (69.5%) | 0.039* |
III–IV | 19 | 1 (5.9%) | 18 (30.5%) | |
TNM stage | ||||
I | 41 | 14 (82.4%) | 27 (45.8%) | 0.028* |
II | 25 | 2 (11.7%) | 23 (38.9%) | |
III | 10 | 1 (5.9%) | 9 (15.3%) | |