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Table 1 Mechanism of natural agents that induce autophagy and apoptosis in cancer cells

From: Natural agents mediated autophagic signal networks in cancer

Natural agents Cancer cell line Pathway References
Resveratrol Ovarian cancer cells STAT3 [52]
Ursolic acid Prostate cancer cell Beclin-1/Akt/mTOR [62]
Colorectal cancer cells with p53 mutant JNK [47]
MCF-7 human breast cancer cells EIF2AK3 [63]
Cervical cancer cells TC-1 ATG5 [64]
Tanshione IIA KBM-5 leukemia cells. mTOR/p70S6K/AMPK [68]
Lung cancer 95D cells ROS [40]
Curcumin Human colon cancer HCT116 cells Transcription factor EB (TFEB) [72]
Human melanoma cells AKT/mTOR [75]
Ginsenoside 20(S)-Rg3 Ovarian cancer LC3II, ATG5, and ATG7 [46]
Fisetin Prostate cancer cells mTOR [43]
Oridonin Human cervical carcinoma Hela cells ROS [82]
Honokiol Neuroblastoma cells PI3K/Akt/mTOR [45]
Piperlongumine Myeloid leukemias P38/ROS [88]