Fig. 1

The ratio of CD4⁺/CD8⁺ T-cells among CD3⁺ T-cells in GC patientsvaried for different tissues. Representative flow cytometric dotplots of a patient and a healthy donor were shown in a, b, respectively. Pooled data showing the CD4⁺ /CD8⁺ ratio from GC patients and HDs were illustrated in c. Horizontal bars depict the median of the CD4⁺/CD8⁺ ratio. The ratios of CD4⁺/CD8⁺ T-cells among CD3⁺ T-cells in GC patients between tumor-infiltrating lymphocytes and matched circulating lymphocytes or paraneoplastic tissue were shown in d. The p values were calculated using the pair wised t test. p < 0.05 was considered as statistically significant