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Fig. 5 | Cancer Cell International

Fig. 5

From: Increased expression of MARCH8, an E3 ubiquitin ligase, is associated with growth of esophageal tumor

Fig. 5

a Cell cycle analyses. a-1 Shows DNA histograms of scrambled siRNA treated cells for 72 h and a-2 shows DNA histograms of MARCH8 siRNA treated cells indicating increased cell death, lesser percentage of S-phase cells and more percentage of cells in G2/M phase in MARCH8 knockdown cells. a-3 Stacked bar graph illustrates cell cycle distribution (**p < 0.01 and *p < 0.05). b Knockdown of MARCH8 induces late apoptotic changes and death in KYSE-410 cells (b-2) as compared to scrambled siRNA treated cells (b-1). b-3 Shows percentage of apoptotic cells in scrambled siRNA treated cells and MARCH8 siRNA treated cells as mean ± SD (*p < 0.05). a: Sub G0 phase; b: G0/G1 phase; c: S-phase and d: G2/M phase

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Cancer Cell International

ISSN: 1475-2867

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