Fig. 5From: Hedgehog/Gli1 signaling pathway regulates MGMT expression and chemoresistance to temozolomide in human glioblastomaRepresentative cases of nude mice with GBM xenografts treated with vehicle (a), TMZ (b), cyclopamine (c), or cyclopamine plus TMZ (d). Combined TMZ with cyclopamine treatment led to significant tumor growth inhibition in nude mice with GBM xenografts (e)Back to article page