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Table 2 The validation of molecular docking algorithm (RMSD)

From: Matrine combined with cisplatin synergistically inhibited urothelial bladder cancer cells via down-regulating VEGF/PI3K/Akt signaling pathway

Protein

CDOCKER RMSD (Ã…)

Libdock RMSD (Ã…)

(PI3K)4J6I

0.917

3.790

(AKT2)2JDR

0.695

a

(Caspase-3)2XYH

2.111

2.546

(Bcl-2)4IEH

1.370

8.190

  1. aIn Libdock module, both matrine and cisplatin cannot dock with the targeted protein