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Fig. 4 | Cancer Cell International

Fig. 4

From: MiR-20a-5p suppresses tumor proliferation by targeting autophagy-related gene 7 in neuroblastoma

Fig. 4

ATG7 inhibited cell proliferation and promotes cellular apoptosis in SH-SY5Y cells. a Western blotting validation of siRNAs on ATG7 knockdown. b Effects of ATG7 knockdown on cell proliferation measured by Real-Time cell kinetic analyzer (RTCA) and c quantification. d Representative photographs of colonies formed in 10 days after siRNA1 transfection. e Caspase-3/7 activity in SH-SY5Y cells transfected with ATG7 siRNA1 and siRNA2. Data are expressed as mean ± SD, n = 3. *p < 0.05 vs. control, Student’s t test. siRNA-NC, negative control siRNA

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