Fig. 6
From: MiR-20a-5p suppresses tumor proliferation by targeting autophagy-related gene 7 in neuroblastoma
The putative schematic representation of pathway involved in miR-20a-5p-mediated suppression of cell proliferation in SH-SY5Y cells. MiR-20a-5p recognizes and binds to 3′-UTR of ATG7, repressing ATG7 gene translation. Since ATG7 contribute to autophagosome initiation and completion, which accounts for cell proliferation and anti-apoptosis, miR-20a-5p-mediated ATG7 inhibition thus results in cell proliferation suppression and further apoptosis