Fig. 5

MiR-539 targets LAMA4 and miR-539 mimic could reduce the expression of LAMA4 both at miRNA and protein level. a The 3′UTR of LAMA4 contained the complementary sequences of miR-539. b Transfection of 293T cells with miR-539 mimic changed the LAMA4-regulated luciferase activity, *p < 0.05. c Upregulation of miR-539 reduced the expression of LAMA4 in mRNA level, *p < 0.05, N = 4, Student t test. d Upregulation of miR-539 reduced the expression of LAMA4 in protein level, *p < 0.05, N = 4, Student t test