Fig. 3
From: RRS1 gene expression involved in the progression of papillary thyroid carcinoma
Microarray assay of RRS1 knock-down cells revealed dramatic alterations of the cancer cell transcriptome. a Heatmap of the 1127 genes altered in both negative control and RRS1 silencing, showing up- (red) and down- (green) regulated genes. b Pie chart showing 489 up- (red) and 683 down- (blue) regulated genes as calculated by both DESeq2 and edgeR algorithms with cutoffs as indicated. c Dot plots of IPA diseases and functions enriched in both knock-downs were shown in dots scaled by − log (P)