Table 1 Comparative analysis of cell death (%) of monolayer and spheroid ACC cells analyzed by MTS assay
| Â | Monolayer | Spheroids | ||
|---|---|---|---|---|
Treatmenta | ||||
 Mitotane | 10 μM | 30 μM | 10 μM | 30 μM |
| Â | 0 | 86.9 | 0 | 15.4 |
 Mitotaneb |  |  |  | 48.1 |
|  | + Mitotane (10 μM) | + Mitotane (30 μM) | ||
|---|---|---|---|---|
Everolimus (10 μM) | 29.7 | 49.3 | 0 | 32.1 |
Sunitinib (5 μM) | 58.2 | 76.2 | 20.3 | 23.6 |
Zol Acid (10 μM) | 19.5 | 30.1 | 0 | 0 |
Imatinib (10 μM) | 27.2 | 50.3 | 0 | 18.1 |
Nilotinib (10 μM) | 62.8 | 70.2 | 39.6 | 56.0 |
Nilotinibb (10 μM) | 67.2 | 62.5 | 62.0 | 60.0 |