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Table 2 Regulation of aberrant expression of FBP1 in cancer

From: Targeting FBPase is an emerging novel approach for cancer therapy

Regulator Interaction Reference(s)
LSD1 Promoter methylation [114]
NF-kappaB Promoter methylation [26]
NPM1 Promoter methylation [28]
Snail-G9a-Dnmt1 Promoter methylation [22]
ZEB1 Promoter methylation [13]
HDAC1/2 Histone deacetylation [81]
Copy number loss Genomic alterations [15, 86]
TRIM28 Ubiquitination degradation [80]
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