Fig. 6
From: MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing’s sarcoma cells
Suppression of ES tumor growth by anti-miR-181c and FAS vector in vivo. a Four groups of mice inoculated with (1) untreated SKES1 cells (n = 7); (2) transfected with negative control-miR (n = 7); (3) transfected with anti-miR-181c (n = 7); and (4) transfected with FAS expression vector (n = 7) were generated. Tumor volumes were measured every 3 days during the treatment. **p < 0.01. b Immunohistochemistry image analysis of FAS and cleaved caspase 3 following the transfection of anti-miR-181c and FAS vector. c The number of FAS and cleaved caspase 3 positive cells per unit area. Data represents represent the mean ± SD of three independent experiments. p < 0.05 was considered to indicate significance: *p < 0.05, **p < 0.01