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Fig. 1 | Cancer Cell International

Fig. 1

From: A cross-talk between integrin β4 and epidermal growth factor receptor induces gefitinib chemoresistance to gastric cancer

Fig. 1

Integrin β4 associates with sensitivity of gefitinib of gastric cancer cell lines. a The sensitivity of the gastric cancer cell lines to gefitinib was assayed by MTT (n = 6). SGC7901R cells exhibited obvious resistance to gefitinib. b The proliferation of SGC7901R and SGC7901 was assayed by MTT (n = 6). The proliferation of SGC7901R was significantly up-regulated. c The resistant gene P-gp was assayed by real-time PCR. The expression of P-gp was increased significantly in SGC7901R cells. d The expression of integrin β4 was assayed by western blot (n = 4). The expression of integrin β4 was up-regulated in SGC7901R cells

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