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Fig. 8 | Cancer Cell International

Fig. 8

From: microRNA-338-3p inhibits proliferation, migration, invasion, and EMT in osteosarcoma cells by targeting activator of 90 kDa heat shock protein ATPase homolog 1

Fig. 8

AHSA1 overexpression attenuates the effects of miR-338-3p on migratory and invasive capacities, and the expression of Vimentin and E-cadherin of osteosarcoma cells. MG-63 and Saos2 cells were transfected with miR-338-3p plus pcDNA-AHSA1, pcDNA3.0 vector plus miR-338-3p, or NC plus pcDNA3.0. Transwell assay was performed to measure the migratory and invasive capacities of MG-63 (a) and Saos2 (b) cells. Left image shows representative results of migration or invasion capacities of cells from each treatment group. Right image shows the average number of migrated or invading cells per field in each treatment group. Data are expressed as mean ± SD, *P < 0.05. Western blot was carried out to detect the expression of Vimentin and E-cadherin in MG-63 (c) and Saos2 (d) cells

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