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Table 2 Subgroup analysis and the pooled RR for patients

From: Allogeneic stem-cell transplantation for multiple myeloma: a systematic review and meta-analysis from 2007 to 2017

Outcomes

No. of studies

Heterogeneity (I2), %

RR (95% CI)

p for heterogeneity

OS

 Auto-allo vs only-allo

2

0

1.28 (1.11, 1.49)

0.435

 Auto-allo vs tandem auto

6

79

0.91 (0.77, 1.06)

0.000

 MA vs RIC

4

38.8

1.14 (0.95, 1.36)

0.179

 High-risk vs standard-risk

5

0

0.83 (0.67, 1.03)

0.599

 First-line vs salvage therapy

4

42.6

1.42 (1.14, 1.78)

0.156

PFS

 Auto-allo vs only-allo

3

17.6

1.46 (1.19, 1.80)

0.297

 Auto-allo vs tandem auto

5

79.9

1.27 (0.84, 1.93)

0.001

 MA vs RIC

4

61.9

1.32 (0.95, 1.83)

0.049

 High-risk vs standard-risk

5

6.1

0.89 (0.66, 1.20)

0.372

 First-line vs salvage therapy

4

0

2.80 (1.97, 3.97)

0.948

TRM

 Auto-allo vs only-allo

2

0

0.41 (0.27, 0.61)

0.420

 Auto-allo vs tandem auto

3

0

6.09 (2.92, 12.7)

0.999

 MA vs RIC

4

26.0

1.48 (1.14, 1.92)

0.256

RR

 Auto-allo vs only-allo

3

75.9

0.80 (0.51, 1.24)

0.016

 Auto-allo vs tandem auto

2

48.1

0.63 (0.50, 0.78)

0.165

 MA vs RIC

3

65.6

0.64 (0.43, 0.95)

0.055