Fig. 3
From: Integrin β1 regulates the invasion and radioresistance of laryngeal cancer cells by targeting CD147
Effects of integrin β1 inhibition on the invasiveness of laryngeal cancer Hep-2 cells. To knockdown the expression of integrin β1, three double-stranded siRNAs targeting integrin β1 or negative control siRNA (NC) were transfected into Hep-2 cells. a The mRNA expression of integrin β1 was analyzed by qPCR. b The protein expression of integrin β1 was analyzed by western blotting. GAPDH was used as an internal control. The siRNA-2 exhibited the most obvious inhibitory effects and was employed in the following experiments. c The migratory ability was analyzed by wound healing assay. d The invasive ability was analyzed by transwell assay. *p < 0.05; #p > 0.05 compared with each control Hep-2 cells