Fig. 5
From: ETS1 is associated with cisplatin resistance through IKKα/NF-κB pathway in cell line MDA-MB-231
IKKα promoter activity and mRNA expression were regulated by ETS1 binding. a Indicated the presence of ETS1 transcription factor putative-binding sites that cluster into four main regions; b luciferase reporter assay revealed that IKKα-Luc in 231/DDP-NC was higher than 231/DDP-KD. c ChIP was performed using an anti-ETS1 antibody or a negative control IgG antibody in 231/DDP and 231/wt cells. Immunoprecipitated DNA was subjected to RT-qPCR using specific IKKα primers that included the ETS1 binding sites