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Table 4 Cumulative effects of rs4848320-T and rs1110839-G on lung cancer and non-small cell lung cancer susceptibility

From: Polymorphism in lncRNA AC016683.6 and its interaction with smoking exposure on the susceptibility of lung cancer

Variant Controls (%) (593) Lung cancer Non-small cell lung cancer
Cases (%) (434) ORa (95% CI) P value Cases (%) (331) ORa (95% CI) P value
No. of alleles
 0 (ref) 232 (39.1) 168 (38.7) 1.00 (ref)   129 (39.0) 1.00 (ref)  
 1 174 (29.3) 115 (26.5) 0.893 (0.654–1.218) 0.474 85 (25.7) 0.871 (0.619–1.225) 0.427
 2 132 (22.3) 112 (25.8) 1.167 (0.846–1.612) 0.346 88 (26.6) 1.207 (0.852–1.710) 0.291
 3–4 55 (9.3) 39 (9.0) 0.985 (0.622–1.560) 0.948 29 (8.8) 0.947 (0.572–1.569) 0.833
Trend    Pb = 0.893    Pb = 0.964  
 0 232 (39.1) 168 (38.7) 1.00 (ref)   129 (39.0) 1.00 (ref)  
 1–4 361 (60.9) 266 (61.3) 1.007 (0.780–1.301) 0.955 202 (61.0) 1.005 (0.761–1.328) 0.971
  1. OR odds ratio, CI confident interval
  2. ORa was adjusted by age, gender and smoking
  3. b P value was calculated by linear-by-linear association of χ2 test