SNP | Genotype | Smoking exposure | Controls (%) | Cases (%) | ORª (95% CI) | P value |
---|---|---|---|---|---|---|
Rs4848320 | CC | Ever | 88 (74.6) | 58 (60.4) | 1.00 (ref) | Â |
CT |  | 29 (24.6) | 32 (33.3) | 1.695 (0.922–3.119) | 0.090 | |
TT |  | 1 (0.8) | 6 (6.3) | 8.219 (0.957–70.618) | 0.055 | |
CT + TT vs CC |  |  |  | 1.929 (1.070–3.479) | 0.029 | |
TT vs CT + CC |  |  |  | 7.048 (0.827–60.092) | 0.074 | |
CC | Never | 314 (66.1) | 233 (68.9) | 1.00 (ref) | Â | |
CT |  | 146 (30.7) | 99 (29.3) | 0.914 (0.671–1.245) | 0.568 | |
TT |  | 15 (3.2) | 6 (1.8) | 0.563 (0.213–1.484) | 0.245 | |
CT + TT vs CC |  |  |  | 0.882 (0.653–1.192) | 0.415 | |
TT vs CT + CC |  |  |  | 0.578 (0.220–1.519) | 0.266 | |
Rs1110839 | TT | Ever | 50 (42.4) | 30 (31.3) | 1.00 (ref) | Â |
TG |  | 62 (52.5) | 53 (55.2) | 1.376 (0.763–2.482) | 0.288 | |
GG |  | 6 (5.1) | 13 (13.5) | 3.224 (1.089–9.544) | 0.034 | |
TG + GG vs TT |  |  |  | 1.539 (0.867–2.731) | 0.141 | |
GG vs TG + TT |  |  |  | 2.652 (0.954–7.371) | 0.062 | |
TT | Never | 200 (42.1) | 144 (42.6) | 1.00 (ref) | Â | |
TG |  | 212 (44.6) | 156 (46.2) | 1.010 (0.748–1.364) | 0.950 | |
GG |  | 63 (13.3) | 38 (11.2) | 0.847 (0.534–1.341) | 0.478 | |
TG + GG vs TT |  |  |  | 0.973 (0.731–1.294) | 0.849 | |
GG vs TG + TT |  |  |  | 0.842 (0.546–1.299) | 0.437 |