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Table 3 Stratified analysis of SNP rs61991156 with clinicopathological parameters of GC

From: rs61991156 in miR-379 is associated with low capability of glycolysis of gastric cancer by enhanced regulation of PKM2

Features

Genotype

AA

AG

GG

AG vs. GG

P value*

AA vs. GG

P value*

Age (years)

   

0.2366

0.4974

 ≤ 50

121

174

81

  

 > 50

157

246

92

  

Gender

   

0.7033

0.0931

 Male

119

139

60

  

 Female

159

281

113

  

H. Pylori infection

   

0.0728

< 0.0001

 Positive

172

341

151

  

 Negative

106

79

22

  

Differentiation

   

< 0.0001

< 0.0001

 G1

6

64

59

  

 G2

61

125

65

  

 G3

96

139

10

  

 G4

94

89

36

  

 Gx

21

3

3

  

Tumor size (cm)

   

0.587

< 0.0001

 ≤ 5

102

341

144

  

 > 5

176

79

29

  

Metastasis

   

< 0.0001

< 0.0001

 Yes

164

202

46

  

 No

114

218

127

  
  1. * Two-sided Chi square test for either genotype distributions or allele frequencies between cases and controls
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Cancer Cell International

ISSN: 1475-2867

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