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Fig. 5 | Cancer Cell International

Fig. 5

From: miR-145 and miR-497 suppress TGF-β-induced epithelial–mesenchymal transition of non-small cell lung cancer by targeting MTDH

Fig. 5

miR-145 and miR-497 directly target MTDH. a, b The potential binding sites of miR-145/miR-497 and MTDH were predicted by bioinformatics tools Starbase v2.0 and Targetscan. c, d Relative luciferase activity in cells co-transfected with wild-type/mutant plasmid and miR-145/miR-497 mimic were evaluated. e–h The expression levels of MTDH in A549 and H1299 cells transfected with miR-145/miR-497 mimic or inhibitor. i, j The mRNA levels of MTDH in A549 and H1299 cells transfected with miR-145/miR-497 mimic or inhibitor. (**P < 0.05)

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Cancer Cell International

ISSN: 1475-2867

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