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Table 1 Clinical characteristic of HCC patients and cancer-free controls

From: Circ-ZEB1.33 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6

Features Cases (n = 64) Controls (n = 30) P* P #
N % N %
Age (years)      0.805 0.743
 ≤ 50 36 56.25 16 53.33   
 > 50 28 43.75 14 46.67   
Gender      0.248 0.321
 Male 42 65.63 15 50.00   
 Female 22 34.38 15 50.00   
HBV infection      < 0.0001 0.145
 Positive 58 90.63 5 16.67   
 Negative 6 9.38 25 83.33   
TMN stage       0.012
 I 12 18.75     
 II 22 34.38     
 III 17 26.56     
 IV 13 20.31     
Tumor size (cm)       0.004
 ≤ 5 37 57.81     
 > 5 27 42.19     
Metastasis       0.143
 Yes 27 42.19     
 No 37 57.81     
  1. * Two-sided Chi square test for different features between cases and controls
  2. # The student’s t-test for circ-ZEB1.33 expression among different features of HCC patients