Fig. 1

The expression of miR-876-5p and vimentin expression in HNSCC cell lines and HNSCC tissues. a The relative miR-876-5p mRNA expression in HNSCC tissues with associated regional nodal metastases and without metastatic primary tumors in situ. b A potential miR-876-5p binding site in the 3′-UTR of vimentin was predicted using TargetScan7.1. c The relative vimentin mRNA expression levels in metastatic HNSCC tissues and non-metastatic HNSCC tissues. d, e The miR-876-5p and vimentin expression level in HN4, HN6 and CAL27 cells. f Differences in the invasiveness of HN4, HN6 and CAL27 cells. The images were captured at × 200 magnification. *P < 0.05, **P < 0.01, ***P < 0.001