Fig. 5

Vimentin is a critical mediator of miR-876-5p in HNSCC cells. a Co-transfection of miR-876-5p mimics with vimentin overexpression restored vimentin expression to the original level in HNSCC cells. b–e MiR-876-5p mimics decreased HNSCC cell invasion and migration, whereas co-transfection with EX-vimentin-M02 negated these changes. The wound area of scratch assays images were captured at ×40 magnification. The images of transwell assays were captured at ×200 magnification. *P < 0.05, **P < 0.01, ***P < 0.001