Fig. 4

CCL18 participates in M2-like TAMs mediated metastasis of SCCHN in vitro. Tu686 cells cultured with M2 CM or M0 CM in the presence or absence of an anti-CCL18 neutralizing antibody at 15 μg/mL, or an isotype-matched IgG protein. Wounding-healing assays (a, b) and Transwell chamber assays (c, d) were used to measure the changes in migration and invasion of Tu686 cells. Data are shown as mean ± SD. **P <0.01, ****P < 0.0001