Fig. 5
From: Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significance
B7-H6 knockdown significantly decreased the expression of C-myc, C-fos and cyclin D1 in HCC cell lines. a Western blotting was performed to examine the protein expression levels of C-myc, C-fos and cyclin D1, which are involved in the regulation of cell proliferation and the cell cycle. b. Statistical analysis showed that in both HepG2 and SMMC-7721 cells, B7-H6 knockdown could significantly decrease the expression of C-myc (both P < 0.01), C-fos (both P < 0.01) and cyclin D1 (P < 0.05 and P < 0.01, respectively)