Fig. 3

BC094916 overexpression suppressed tumor progression in the SP 2/0 xenograft mouse model. The stable BC094916- and EGFP-expressing SP 2/0 cells (BC094916) and only EGFP-expressing SP 2/0 cells (vector) were subcutaneously injected into Balb/C (4 mice/group) mice. a Tumor size from three independent experiments (n = 12 mice/group) was monitored every day by determining tumor volumes. b–d Pictures of subcutaneous tumor tissues b from one experiment (n = 4 mice/group), tumor weights (c) and tumor volumes (d) from three independent experiments (n = 12 mice/group) on day 8 after SP 2/0 xenograft. a, c, d Data are shown as mean ± SEM (n = 12) from three independent experiments. Two tailed Student’s t-test, **P < 0.01, ****p < 0.0001