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Table 2 BC094916 mRNA expression decreased in LPS-induced plasma cells

From: BC094916 suppressed SP 2/0 xenograft tumor by down-regulating Creb1 and Bcl2 transcription

Gene symbol

Fold change

Regulation

Experiment 1

Experiment 2

Prdm1

34.05

27.52

Up

Xbp1

10.17

8.79

Up

Pax5

0.09

0.29

Down

Bcl6

0.16

0.17

Down

BC094916

0.04

0.11

Down

  1. The splenocytes were separated from three C57BL/6 mice per group. B cells were sorted by B220 microbeads, and stimulated for 3 days in vitro by 10 μg/ml LPS. The transcripts in LPS-stimulated B cells were determined by Affymetrix Microarrays. The fold change of the transcripts in LPS-stimulated group to unstimulated group is shown from 2 separate experiments