Skip to main content

Table 6 BC094916 overexpression suppress the expression of anti-apoptosis, eukaryotic translation initiation factor (Eif) and eukaryotic translation elongation factor (Eef) gene in SP 2/0 cells

From: BC094916 suppressed SP 2/0 xenograft tumor by down-regulating Creb1 and Bcl2 transcription

Gene symbol Total exon fragments FPKM
Vector BC094916 Fold change Vector BC094916 Fold change
BC094916 1.00 93.00 93.00 0.03 2.97 99.00
prdm1 1738.00 1280.00 0.74 19.86 16.59 0.84
Xbp1 6951.81 6944.75 1.00 173.37 197.54 1.14
Bcl6 223.71 125.99 0.56 3.37 2.16 0.64
Trp53 5333.00 4871.00 0.91 156.64 163.57 1.04
Bcl2 44.00 27.06 0.61 0.34 0.23 0.68
Bcl2l1 1499.00 954.00 0.64 37.95 29.11 0.77
Mcl1 35841.98 19278.00 0.54 850.34 493.80 0.58
Eif4a2 10798.10 7854.01 0.73 344.03 281.28 0.82
Eif5b 241.50 77.26 0.32 22.18 8.10 0.37
Eif4e2 989.06 507.78 0.51 42.48 24.37 0.57
Eif2s3x 307.22 0.00 0.00 14.79 0.00 0.00
Eef1b2 14673.00 9209.01 0.63 654.39 457.86 0.70
Eef1d 1175.02 582.81 0.50 90.55 51.18 0.57
Creb1 233.00 55.00 0.24 4.78 0.82 0.17
  1. RNA-seq was done with an Illumina HiSeq 2500 instrument at GENEWIZ, Suzhou, China. Total exon fragments and FPKM (FPKM = total exon fragments/mapped reads (millions)/exon length (KB), Fragments per Kilo bases per Million reads) values of selected genes encoding prdm1, Xbp1, Pax5, Bcl6, Trp53, Bcl2l1, Bcl2l1, Mcl1, Eif4a2, Eif5b, Eif4e2, Eif2s3x, Eef1b2, Eef1d, and Creb1, and the fold change of gene expression in BC094916-overexpressed SP 2/0 cells to control SP 2/0 cells are shown