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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA DLX6-AS1 promoted cancer cell proliferation and invasion by attenuating the endogenous function of miR-181b in pancreatic cancer

Fig. 2

Knockdown of lncRNA DLX6-AS1 suppressed pancreatic cancer cell proliferation, migration and invasion. a The expression of DLX6-AS1 in human pancreatic cancer cell lines and human pancreatic duct epithelial cell line (HPDE6-C7) was determined by qRT-PCR. b DLX6-AS1 siRNAs [siDLX6-AS1 and siDLX6-AS1(a)] transfection suppressed the expression of DLX6-AS1 in SW1990 cell sand PANC-1 cells. The cell proliferation of c SW1990 cells and d PANC-1 cells transfected with siNC, siDLX6-AS1 or siDLX6-AS1(a) was determined by CCK-8 assay. e Colony formation assay was performed to analyze the cell growth of SW1990 and PANC-1 cells transfected with siNC or siDLX6-AS1. f Cell migration and g cell invasion of SW1990 and PANC-1 cells transfected with siNC or siDLX6-AS1 were determined by Transwell migration assay and Transwell invasion assay, respectively. *P < 0.05, **P < 0.01 and ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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