Fig. 5
From: A drug screening assay on cancer cells chronically adapted to acidosis
pH and light-dependent activity of VP on cancer cells. Viability assay (a) and clonogenic assay (b) show that AA-HCT116 are more sensitive than HCT116 cells to VP. Data from viability assay in A were obtained from 5 different experiments and means and SEM are shown. HCT116 MCS are sensitive to the cytotoxic activity of VP as shown by viability assay (c) and clonogenic assay (d). The cytotoxic activity of VP was tested in conditions of darkness (e) and ambient light (f) in HCT116 and AA-HCT116 cells. Data from at least two independent experiments are shown