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Fig. 6 | Cancer Cell International

Fig. 6

From: A drug screening assay on cancer cells chronically adapted to acidosis

Fig. 6

pH-dependent intracellular accumulation of VP. a Dose-dependent intracellular accumulation of VP was analysed by fluorimetry in HCT116 and AAHCT116 cells and normalised to protein content. b HCT116 and AA-HCT116 cells were treated with VP for 30 min and analysed by confocal microscopy. Scale bar 10 μm. c Intracellular accumulation of VP was analysed by fluorimetry in HCT116 cells transiently exposed to medium at pH 7.4 or pH 6.8 for 4 h. *P<0.05

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