Fig. 4
From: Paraoxonase 3 is involved in the multi-drug resistance of esophageal cancer
Effects of a forced reversal of the PON3 levels on the drug resistance of K150 cells. Representative areas of K150 cells transfected with GFP-PON3 ectopic expression construct were shown and GFP was used as a negative control (a). PON3 protein (b) and mRNA (c) level determined by western blot and qRT-PCR analysis in the GFP-tagged overexpression construct-transfected versus the NC-transfected K150. The cell death triggered by an IC50 dose of four drugs in K150 cells transfected with the GFP-PON3-transfected versus the negative control (NC) assayed 72Â h after treatment with the IC50 dose of drugs (d)