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Fig. 4 | Cancer Cell International

Fig. 4

From: Biological indicators of chemoresistance: an ex vivo analysis of γH2AX and p53 expression in feline injection-site sarcomas

Fig. 4

Validation of cell lines with sarcoma formation in nude mice or through detection of vimentin. Histological sections stained with hematoxylin and eosin from sarcomas that formed at the site of subcutaneous injection of E9 (A) and G4-1 (B) FISS cells. Results from C10 and J1/3-1 were similar. FISS cells from lines that were not validated by documentation of sarcoma formation in nude mice were validated via detection of vimentin expression. Results were similar for all 7 cell lines (D9, M3, N3-1, Q8-1, Sh4, O7, Y5). Depicted are representative results for D9 (C). D The corresponding negative control. Scale bars = 200 µm

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