Fig. 2
From: MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma
miR-770 inhibits human glioma U251 cell proliferation and induces G1-S cell cycle arrest and apoptosis. a miR-770 expression was detected in U251 cells after miR-770 overexpression. b miR-770 expression was examined in U251 cells after anti-miR-770 treatment. c miR-770 overexpression decreased cell activity at 48 and 72 h after transfection. d Anti-miR-770 increased cell activity at 48 and 72 h after transfection. e miR-770 overexpression suppressed glioma cell proliferation. f Anti-miR-770 promoted glioma cell growth. g The histogram represents the proportion of cells in the G0/G1, S and G2/M phases after miR-770 overexpression. h The ratio of cells in the G0/G1, S and G2/M phases after anti-miR-770 transfection. i The data revealed the ratios of early and late apoptosis after miR-770 overexpression. j The data showed the proportions of early apoptosis and late apoptosis after anti-miR-770 transfection. *p < 0.01, n = 3