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Fig. 3 | Cancer Cell International

Fig. 3

From: MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma

Fig. 3

miR-770 directly targets the CDK8 gene. a Bioinformatics predicted interactions of miR-770 and its binding sites in the 3′-UTR of CDK8. b Luciferase activity was examined by the dual-luciferase assay. c CDK8 mRNA expression in human glioma tissues. d CDK8 protein levels were measured by Western blotting. e miR-770 and CDK8 levels were inversely correlated. The 2−ΔΔCt values of miR-770 and CDK8 were subjected to a Pearson correlation analysis (n = 63, r = − 0.5638, p < 0.001, Pearson’s correlation). *p < 0.01

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