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Table 3 Correlation between density scores of IL-33-IR/ST2-IR positive cells and TNM stage, node involvement and invasion depth in patients with ESCC

From: Cellular and clinicopathological features of the IL-33/ST2 axis in human esophageal squamous cell carcinomas

Parameters

IL-33-IR positive cell density scores

ST2-IR positive cell density scores

ESCC

Stroma

ESCC

Stroma

TNM stage

 I + II

2.0 (0.87–2.53)

1.5 (0.90–1.90)

2.0 (1.27–2.53)

2.0 (1.52–2.48)

 III

3.0 (2.30–2.77)

3.0 (2.14–2.72)

3.0 (2.08–2.78)

3.0 (2.41–2.82)

 P value

< 0.05

< 0.01

< 0.05

< 0.05

Node involvement

 Positive

2.5 (1.93–3.08)

3.0 (2.41–3.26)

3.0 (2.13–3.21)

2.0 (1.93–3.08)

 Negative

3.0 (2.02–2.61)

2.0 (1.73–2.32)

3.0 (1.89–2.58)

2.0 (2.24–2.70)

 P value

> 0.05

< 0.05

< 0.05

< 0.05

Invasion depth

 Muscular

3.0 (1.49–3.26)

1.5 (1.00–2.25)

2.5 (1.51–2.99)

2.0 (1.55–2.45)

 All layer

2.0 (1.39–2.29)

2.5 (1.88–2.56)

3.0 (1.99–2.69)

3.0 (2.37–2.82)

 P value

> 0.05

> 0.05

> 0.05

< 0.05

  1. P values were derived from Mann–Whitney tests