Table 1 Clinical manifestations and cytogenetic abnormalities of AML patients stratified by age
Total (n = 179) | Younger patients (n = 111) | Older patients (n = 68) | p value | |
|---|---|---|---|---|
Age, years (median, range) | 53 (18–88) | 44 (18–59) | 67 (60–88) | |
Male (n, %) | 116 (64.8) | 71 (64.0) | 45 (66.2) | 0.872 |
WBC (× 109/L) (median, range) | 7.82 (0.4–362.6) | 8.48 (0.4–362.6) | 7.42 (0.6–271.4) | 0.380 |
Blast cells in BM (%, range) | 53 (10–95) | 57 (10–94.5) | 53 (21–95) | 0.824 |
Complex karyotype | 16/130 (12.3) | 9/81 (11.1) | 7/49 (14.3) | 0.784 |
RUNX1–RUNX1T1 | 18 (10.1) | 16 (14.4) | 2 (2.9) | 0.019 |
CBFβ–MYH11 | 10 (5.6) | 8 (7.2) | 2 (2.9) | 0.322 |