Fig. 4

ESE-15-one and ESE-one exposure does not affect actin cytoskeletal organization but does affect nuclei morphology. Cycling cells or interphase arrested cells were exposed to 0.5 μM ESE-15-one or 0.5 μM ESE-one for 18 h before being fixed and stained for F-actin (red) and nuclei (blue). DMSO was used as vehicle control. Images were obtained on a LSM510 with a ×63 mag objective. Scale bar = 20 μm