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Fig. 5 | Cancer Cell International

Fig. 5

From: Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization

Fig. 5

ESE-15-one and ESE-one exposure stabilize and disorganize microtubules. a MDA-MB-231 cells were either cycling or arrested in interphase and treated with DMSO, ESE-15-one or ESE-one for 18 h after which detyrosinated, stabilized microtubules (a), or tyrosinated, dynamic microtubules (b) (green) were visualized along with cell nuclei (blue). Images were obtained on a LSM510 with a ×63 mag objective. Scale bar = 5 μm

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