Fig. 11

Drugs that lower the expression of JAG2, HPRT1, AURKA, and PGK1. Cell lines (x-axis) were evaluated for their expression of AURKA and HPRT1 pre and post treatment with drugs (y-axis). The relative changes in protein expression are indicated by the heat map legend and show the variety of responses to various drugs. The events and their effects on target gene expression are indicated by the bar graphs