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Fig. 2 | Cancer Cell International

Fig. 2

From: hsa_circ_0081143 promotes cisplatin resistance in gastric cancer by targeting miR-646/CDK6 pathway

Fig. 2

Hsa_circ_0081143 promoted GC cells proliferation, invasion, and cisplatin resistance. a Relative expression of hsa_circ_0081143 in GC cells transfected with si-circ_0081143 and si-NC. b, c Has-circ_0081143 inhibition decreased the proliferation and colony formation ability in GC cells. d Has-circ_0081143 inhibition induced GC cells apoptosis rate. e Has-circ_0081143 inhibition reduced GC cells invasion ability. f Has-circ_0081143 reduction increased the sensitivity of GC cells to cisplatin. g The tumor volumes were measured every week. h Photographs of tumor xenografts excised 6 weeks. i Tumor weight was measured after mouse was surgically dissected. *P < 0.05

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