Table 2 Correlation between PD-L1 expression and clinicopathological features
From: Prognostic role of PD-L1 for HCC patients after potentially curative resection: a meta-analysis
Clinical characteristics | Number of studies | Cases | Odds ratio (95% CI) | P | Heterogeneity | |
|---|---|---|---|---|---|---|
I2 (%) | P | |||||
Gender (male/female) | 11 | 2390 | 1.09 (0.78, 1.51) | 0.62 | 21 | 0.24 |
Age (older/younger) | 8 | 1535 | 0.93 (0.73, 1.19) | 0.58 | 0 | 0.92 |
Hepatitis (yes/no) | 8 | 1799 | 0.68 (0.47, 0.98) | 0.04 | 5 | 0.40 |
Cirrhosis (yes/no) | 6 | 999 | 1.12 (0.74, 1.70) | 0.59 | 30 | 0.20 |
AFP (higher/lower) | 8 | 1432 | 1.43 (1.02, 2.00) | 0.04 | 35 | 0.14 |
Tumour size (larger/smaller) | 8 | 1688 | 1.30 (0.88, 1.92) | 0.19 | 55 | 0.03 |
Tumour encapsulation (no/yes) | 4 | 933 | 0.91 (0.47, 1.77) | 0.79 | 68 | 0.03 |
Tumour number (multiple/single) | 8 | 1731 | 1.05 (0.75, 1.49) | 0.77 | 31 | 0.18 |
Vascular invasion (yes/no) | 9 | 2050 | 1.62 (0.99, 2.64) | 0.06 | 75 | < 0.001 |
TNM stage (advanced/earlier) | 11 | 2169 | 1.04 (0.73, 1.50) | 0.81 | 42 | 0.07 |