Table 1 Basic characteristics of TCGA HCC patients
Clinical features | Overall survival | Disease-free survival | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Patients (n = 360) | No.of events (%) | MST (months) | HR (95% CI) | P value | Patients (n = 310) | No. of events (%) | MST (month) | HR (95% CI) | P value | |
Age (year) | ||||||||||
 < 60 | 165 | 54 (32.7%) | 26.96 | 1.18 (0.83–1.68) | 0.36 | 145 | 78 (53.8%) | 20.54 | 0.78 (0.74–1.36) | 0.98 |
 ≥ 60 | 195 | 75 (38.4%) | 26.39 |  |  | 165 | 92 (55.7%) | 19.75 |  |  |
Sex | ||||||||||
 Male | 243 | 79 (32.5%) | 25.94 | 1.18 (0.82–1.69) | 0.38 | 203 | 114 (56.1%) | 20.29 | 0.84 (0.64–1.22) | 0.45 |
 Female | 117 | 50 (42.7%) | 28.12 |  |  | 97 | 56 (57.7%) | 19.74 |  |  |
Race | ||||||||||
 Asian | 155 | 44 (28.3%) | 25.87 | 0.75 (0.52–1.09) | 0.13 | 138 | 69 (50.0%) | 21.26 | 0.80 (0.59–1.09) | 0.16 |
 White + others | 195 | 80 (41.0%) | 27.51 |  |  | 165 | 98 (59.4%) | 19.37 |  |  |
 Missing | 10 |  |  |  |  | 7 |  |  |  |  |
BMI | ||||||||||
 ≤ 25 | 174 | 62 (35.6%) | 25.30 | 0.74 (0.51–1.06) | 0.10 | 149 | 80 (53.7%) | 18.50 | 0.85 (0.62–1.18) | 0.33 |
 > 25 | 153 | 49 (32.0%) | 29.63 |  |  | 135 | 75 (55.5%) | 23.09 |  |  |
 Missing | 33 |  |  |  |  | 26 |  |  |  |  |
Grade | ||||||||||
 1–2 | 224 | 78 (34.8%) | 27.13 | 1.14 (0.78–1.67) | 0.49 | 192 | 101 (52.6%) | 20.22 | 1.17 (0.85–1.61) | 0.33 |
 3–4 | 131 | 47 (35.8%) | 25.57 |  |  | 114 | 65 (57.1%) | 19.99 |  |  |
 Missing | 5 |  |  |  |  | 4 |  |  |  |  |
TNM stage | ||||||||||
 I–II | 248 | 67 (27.0%) | 28.34 | 2.48 (1.71–3.62) | <0.001 | 215 | 101 (46.9%) | 22.41 | 2.41 (1.72–3.36) | <0.001 |
 III–IV | 88 | 48 (54.5%) | 22.54 |  |  | 74 | 55 (74.3%) | 14.58 |  |  |
 Missing | 24 |  |  |  |  | 21 |  |  |  |  |