Fig. 5
From: Raltitrexed increases radiation sensitivity of esophageal squamous carcinoma cells
Raltitrexed (Ral) sensitized radiation (IR) induced anticancer effect in TE-13 xenografts. a The sizes of xenograft tumors in four different groups, including the control group, Ral group (7.5 mg/kg/day, day 0–4 and day 7–11), IR group (8 Gy day 0), and combination group; b tumor volumes in four groups; c T/C(%), tumor volume of treatment Group (T) compared with the control group (C); d mice weight in the four groups during the treatment; e comparison of tumor weight of the four groups; f, g immunohistochemistry of xenograft tumor for Ki-67 and PCNA. Error bar: standard deviation; *p < 0.05, ***p < 0.001, ****p < 0.0001